Sofia K. Leka, Sofia Kitsiou-Tzeli, Ariadni Kalpini-Mavrou, Emmanuel Kanavakis Horemis Research Laboratory, Department of Medical Genetics, Athens University School of Medicine, “Aghia Sofia” Children’s Hospital, Athens, Greece Abstract Since its discovery in 1997, knowledge about the SHOX gene (Short stature HOmeoboX-containing gene) has rapidly advanced. Although originally described as causing idiopathic short stature, SHOX mutations Read More
Author: admin
The problem of exogenous subclinical hyperthyroidism
Menelaos L. Batrinos Emeritus Professor of Endocrinology, Athens University Medical School, Athens, Greece Abstract Over the past two decades a plethora of publications and clinical practice data have established that subclinical thyroid dysfunction is a common condition occurring much more frequently than the overt expression of thyroid disease. Subclinical hypothyroidism is considered to be the Read More
Early microvascular and macrovascular dysfunction is not accompanied by structural arterial injury in polycystic ovary syndrome
Krystallenia Alexandraki,1 Athanasios D. Protogerou,2 Theodoros G. Papaioannou,2 Christina Piperi,3 George Mastorakos,4 John Lekakis,2 Dimitrios Panidis,5 Evanthia Diamanti-Kandarakis1 1Division of Endocrinology, First Department of Medicine, Laiko Hospital, 2Vascular Laboratory, Department of Clinical Therapeutic, Alexandra Hospital, 3Laboratory of Biological Chemistry, 4Endocrine Unit, Second Department of Obstetrics and Gynecology, Aretaeion Hospital, Athens University School of Medicine, Athens, Read More
Insulin resistance, growth factors and cytokine levels in overweight women with breast cancer before and after chemotherapy
Eftychia Chala,1 Christos Manes,2 Helias Iliades,3 Georgios Skaragkas,2 Despina Mouratidou,3 Efthymios Kapantais1 1Department of Diabetes-Obesity-Metabolism, Metropolitan Hospital, Neo Faliro, Greece, 2Diabetes Center, Papageorgiou Hospital, 33rd Department of Clinical Oncology, Theagenio Hospital, Thessaloniki, Greece Abstract OBJECTIVE: To evaluate insulin values, insulin resistance, growth factors and cytokine levels in women suffering from breast cancer and the effect Read More
Estradiol and progesterone supplementation during luteal phase improved the receptivity of the endometrium in a patient with a history of diethylstilboestrol exposure in-utero
Dimitris Loutradis,1 Konstantinos Stefanidis,1 Erasmia Kiapekou,2 Evangelia Zapanti,2 Chrisoula Panitsa-Faflia,1 Aristidis Antsaklis1 1First Department of Obstetrics and Gynaecology, Athens University School of Medicine, Alexandra Hospital, 2First Endocrine Section, Alexandra Hospital, Athens, Greece Abstract BACKGROUND: Diethylstilboestrol (DES) exposure in-utero has been shown to have negative effects on pregnancy. DES-exposed women are at increased risk of early Read More
Nobel prize winner Christian de Duve. From insulin to lysosomes
Jean-Pierre Tricot Catholic University of Leuven (Belgium) “Neglect of the history of medicine sets in motion the dismal cycle of medical science which, turning almost without metabolism, repeatedly brings to light the same material.” Rudolf Virchow, the founder of cell pathology, (1851) (Presented at the Symposium on the History of Diabetes, Delphi, September 7-9, 2005) Read More
Hermaphroditism in Greek and Roman antiquity
George Androutsos Institute of History of Medicine, University Claude Bernard, Lyon, France Abstract Since antiquity hermaphrodites have fascinated the mind and excited the imagination. In this paper, such subjects are discussed as legends about the nativity of Hermaphroditus, son of Hermes and Aphrodite, the social status of these bisexual beings, and their fate in Greek-Roman Read More
Calciphylaxis: a complication of end-stage renal disease improved by parathyroidectomy
John C. Maroulis,1 Constantinos Fourtounas,2 John G. Vlachojannis,2 Nikolaos Siasos,1 Dionysios Karavias,1 Dionysios Chartoumpekis,3 Ioannis Habeos3 1Department of Surgery, 2Department of Internal Medicine-Nephrology, 3Department of Internal Medicine-Endocrinology, Patras University School of Medicine Abstract A 43-year old Caucasian male with end-stage renal disease presented with painful skin lesions and high calcium phosphate product that did not Read More
The use of insulin sensitising agents in ovulation induction in women with Polycystic Ovary Syndrome
Richard Fleming University of Glasgow and Division of Developmental Medicine, both based at Glasgow Royal Infirmary, G31 2ER, GB Abstract Insulin resistance is an important "upstream" driver for reproductive and metabolic abnormalities in women with Polycystic Ovary Syndrome (PCOS). This theoretical background is now supported by substantial evidence for treating women with PCOS with insulin Read More
Thyroid Nodules 2006: Managing what has been known for over 50 years
Jeffrey R. Garber Division of Endocrinology, Harvard Vanguard Medical Associates, Massachusetts, USA The 50th anniversary of the publication of Mortensen, Woolner and Bennet's paper entitled Gross and microscopic findings in clinically normal thyroid glands has just passed. 1 Their paper reported that at autopsy at the Mayo Clinic approximately half of those not known to Read More