Eleni Kousta1, Natasha J. Lawrence1, Ian F. Godsland1, Anna Penny1, Victor Anyaoku1, Barbara A. Millauer1, Stephen Robinson1, Desmond G. Johnston1, Mark I. McCarthy1,2 1Section of Endocrinology and Metabolic Medicine, 2Imperial College Genetics and Genomics Research Institute, Imperial College Faculty of Medicine, St. Mary’s Hospital, Norfolk Place, London W2 1PG, U.K. Abstract OBJECTIVE: To characterise early Read More
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Data on pubertal development in Greek boys. A longitudinal study
Kyratsoula Pantsiotou National Health Service, Endocrine Clinic Athens, Greece Abstract OBJECTIVE: Longitudinal data on boys' puberty evolution are not available in Greece and very few such studies have been reported world-wide. We present data from a longitudinal study on height, weight, BMI and age at the different pubertal stages in Greek boys. DESIGN: At the Read More
A newly detected mutation of the RET protooncogene in exon 8 as a cause of multiple endocrine neoplasia type 2A
Sotirios Bethanis1, George Koutsodontis2, Theodosia Palouka1, Christos Avgoustis1, Drakoulis Yannoukakos2, Thalia Bei2, Savas Papadopoulos3, Dimitrios Linos4, Stylianos Tsagarakis1 1Department of Endocrinology, Athens Polyclinic, 2BioGenomica, Center for Genetic Research and Analysis, 3Department of Pathology, Hygeia Hospital, 4First Department of Surgery, Hygeia Hospital, Athens, Greece Abstract Multiple endocrine neoplasia type 2A (MEN2A) is a syndrome of familial Read More
Diabetes and the \’Natural Faculties\’ in the Galenic treatises
Niki Papavramidou, Helen Christopoulou-Aletra Department of History of Medicine, Aristotle University School of Medicine, Thessaloniki, Greece The term diabetes first appears in a text by Aretaeus to describe a disease of the kidneys. Galen is likely to have borrowed this term from Aretaeus also to describe the same disorder, though in a manner somewhat uncharacteristic Read More
The spectrum of phytoestrogens in nature: our knowledge is expanding
Paraskevi Moutsatsou Department of Biological Chemistry, Athens University Medical School, Athens, Greece Abstract The classical phytoestrogens, so far known, constitute a group of plant-derived compounds which include mainly isoflavones, lignans, coumestanes, stilbenes and the flavonoids quercetin and kaempherol. The discovery of many more novel estrogen-like compounds in the plant kingdom demonstrates that the spectrum of Read More
Brunner?s missing ?Aha experience? delayed progress in diabetes research by 200 years
Fritz S. Keck1, Leonidas H. Duntas2 1Westkuestenklinikum Heide, Germany, 2Evgenidion Hospital, Athens University School of Medice, Athens, Greece Abstract In 1889, the pancreatectomy performed on a dog by Joseph von Mehring and Oskar Minkowski led to the discovery of the pancreatic origin of diabetes disease. Already 200 years before, Johann Conrad Brunner had successfully performed Read More
Management of thyroid nodules in children and adolescents
Wilmar M. Wiersinga Department of Endocrinology & Metabolism, Academic Medical Center, University of Amsterdam, the Netherlands Abstract Thyroid nodules in childhood and adolescence are less prevalent but more often malignant than in adulthood. Malignant nodules are predominantly papillary cancers; benign nodules are mostly solid colloid nodules/adenomas, but can be cystic or due lymphocytic thyroiditis. Previous Read More
Differentiated thyroid cancer in children and adults: same or distinct disease?
Barbara Jarzab, Daria Handkiewicz-Junak Department of Nuclear Medicine and Endocrine Oncology, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland Abstract Differentiated thyroid cancer (Dtc) is a rare disease, especially in children. Differences in the biology and clinical course of Dtc in children, when compared with adults, may be related both Read More
Early onset adiposity: A pathway to polycystic ovary syndrome in adolescents?
Evanthia Diamanti-Kandarakis, Charikleia D. Christakou, Eleni Kandaraki, Krystallenia I. Alexandraki First Department of Medicine, Endocrine Section, Athens University School of Medicine, Athens, Greece Abstract Polycystic Ovary Syndrome is a heterogenous syndrome of unknown causation commonly associated with obesity. Τhe particular timing of the onset of obesity may be important, since the earlier the onset of Read More
Contribution of endocrine parameters in predicting outcome of multiple trauma patients in an intensive care unit
Ioannis Ilias1, Konstantinos Stamoulis2, Apostolos Armaganidis2, Panagiotis Lyberopoulos2, Marinella Tzanela3, Stylianos Orfanos2, Maria Theodorakopoulou2, Stylianos Tsagarakis4, Ioanna Dimopoulou2 1Department of Endocrinology, Elena Venizelou Hospital, 2Second Department of Critical Care Medicine, Attikon Hospital, Athens University School of Medicine, 3Department of Endocrinology, Evangelismos Hospital, and 4Department of Endocrinology, Athens Polyclinic, Athens, Greece Abstract OBJECTIVE: To evaluate whether Read More