Michael Hermanussen Privat Dozent Dr. med., Aschauhof, 243 40 Altenhof, Germany Abstract The ancestors of modern Europeans arrived in Europe at least 40,000 years before present. Pre-glacial maximum Upper Palaeolithic males (before 16,000 BC) were tall and slim (mean height 179 cm, estimated average body weight 67 kg), while the females were comparably small and Read More
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The use of recombinant human thyrotropin (Thyrogen) in the diagnosis and treatment of thyroid cancer
Leonidas H. Duntas1, Nikolaos Tsakalakos2, Brigitte Grab-Duntas3, Maria Kalarritou1, Elli Papadodima4 1Endocrine Unit, Evgenidion Hospital, University of Athens Medical School, 2Iaso General Hospital, 3Institute of Isotopic Studies, 4Henry Dunant Hospital, Athens, Greece Abstract The introduction of human recombinant thyrotropin (rhTSH/Thyrogen) into the diagnosis of thyroid cancer has substantially ameliorated the patient's quality of life through Read More
GH deficiency in adults
Dimitrios S Papadogias1, Polyzois Makras1, Gregory A Kaltsas1,2, John P Monson2 Departments of Endocrinology, 1G. Gennimatas General Hospital, Athens Greece, 2St Bartholomew's Hospital, London EC1A 7BE, UK Abstract Until the last decade, the diagnosis of GH deficiency (GHD) in adults was only considered as a marker of hypothalamo-pituitary disease. GHD in adults is now recognized Read More
The-2548G/A polymorphism in the human leptin gene promoter region is associated with plasma free leptin levels; interaction with adiposity and gender in healthy subjects
Nikos Yiannakouris1, Labros Melistas1, Mary Yannakoulia1, Keisha Mungal2, Christos S. Mantzoros2 1Departments of Home Economics and Ecology and Nutrition-Dietetics, Harokopio University, 176 71 Athens, Greece, 2Division of Endocrinology and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA Abstract A common -2548G/A promoter variant of the human leptin Read More
Effect of Restoration of Euthyroidism on Peripheral Blood Cells and Erythropoietin in Women with Subclinical Hypothyroidism
Mirjam Christ-Crain1, Christian Meier1, Peter Huber2, Henryk Zulewski1, Jean-Jacques Staub1, Beat Müller1 1Division of Endocrinology, Diabetes, and Clinical Nutrition, Department of Internal Medicine, and 2Department of Central Laboratories, University Hospitals, CH-4031 Basel, Switzerland Supported by grants from the Swiss National Science Foundation (32.27866.89, 32.37792.93, and 32.37792.98) and unconditional research grants from Henning Berlin, Novartis, Roche Read More
The Influence of Serum Cortisol Levels on Growth Hormone Responsiveness to GH-Releasing Hormone Plus GH-Releasing Peptide-6 in Patients with Hypocortisolism
Sandra Pekic1, Mirjana Doknic1, Marina Djurovic1, Svetozar Damjanovic1, Milan Petakov1, Dragana Miljic1, Carlos Dieguez2, Felipe F Casanueva3, Vera Popovic1 1Institute of Endocrinology, University Clinical Center, Belgrade, Yugoslavia, 2Department of Physiology and 3Department of Medicine, Faculty of Medicine, University of Santiago de Compostela, Santiago de Compostela, Spain Abstract The aim of this study was to evaluate Read More
Cancer in the thyroid is not always thyroid cancer
Katherine E. Akester1, Noel Somasundaram1, Salvador Diaz-Cano2, Ashley B. Grossman1 Departments of 1Endocrinology and 2Histopathology, St. Bartholomew's Hospital, London EC1A 7BE, UK Abstract Most clinicians assume that a thyroid mass which appears to be malignant is most likely a tumour arising from thyroid cells. We present a case where the thyroid malignancy was associated with Read More
Pituitary Hyperplasia
Mubarak Al-Gahtany1, Eva Horvath2, Kalman Kovacs3 1Department of Neurosurgery, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada, 2&3 Department of Laboratory Medicine, St. Michael Hospital, University of Toronto, Toronto, Ontario, Canada Abstract Pituitary hyperplasia is rare, difficult to diagnose and sometimes controversial. The hyperplasia could be physiologic which is usually reversible, or pathologic which Read More
The treacherous use of thyroxine preparations. Stability of thyroxine preparations
Demetrios A. Koutras Endocrine Unit, "Evgenidion Hospital", Athens University Medical School, Athens, Greece Endocrinologists not infrequently confront the problem of inconsistent blood values of thyroxine among patients receiving L-thyroxine preparations. The question is how universal this problem is. Before the use of L-thyroxine or thyroid gland preparations, hypothyroid patients were left untreated. It was therefore Read More
Relative Iron \”Overload\” in Offspring of Patients with Type 2 Diabetes Mellitus: A New Component in the Conundrum of Insulin Resistance Syndrome?
Agathoklis Psyrogiannis1, Venetsana Kyriazopoulou1, Argiris Symeonidis2, Michalis Leotsinidis3, Apostolos G. Vagenakis 1Department of Medicine, Division of Endocrinology and Diabetes, 2Division of Hematology, 3Department of Public Health, University of Patras Medical School, Patras, Greece Abstract There are a few reports suggesting that subtle disturbances of iron metabolism are frequently found in patients with type 2 diabetes Read More