Sílvia Paredes,1,2 Claudia Matta-Coelho,1,3 Ana Margarida Monteiro,1 Alice Brás,2 Olinda Marques,1 Marta Alves,1 Laura Ribeiro2,4,5 1Department of Endocrinology, Hospital de Braga, Portugal; 2Department of Medical Education and Simulation, Faculty of Medicine, University of Porto, Portugal; 3Faculty of Nutrition and Food Sciences, University of Porto, Portugal; 4Department of Biochemistry, Faculty of Medicine, University of Porto, Portugal; Read More
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Effects of ghrelin in energy balance and body weight homeostasis
Laura Mihalache,1 Andreea Gherasim,1 Otilia Niță,1 Maria Christina Ungureanu,1 Sergiu Serghei Pădureanu,2 Radu Sebastian Gavril,1 Lidia Iuliana Arhire1 1Department of Internal Medicine, 2Department of Surgery, “Grigore T. Popa” University of Medicine and Pharmacy, Iassy, Romania Abstract Ghrelin is a gut peptide composed of 28 amino acids mostly secreted in the gastric fundus mucosa. It was Read More
Comparison of color-Doppler and qualitative and quantitative strain-elastography for differentiation of thyroid nodules in daily practice
Manuela Götzberger,1 Susanne Krueger, 2 Roland Gärtner,1 Martin Reincke,1 Matthias Pichler,1 Gerald Assmann,3 Thomas Mussack,4 Michael Zimmermann5, Veit Gülberg1 1Medizinische Klinik und Poliklinik IV, Klinikum der Universität München; 2Klinikum Bogenhausen; 3Pathologisches Institut, Klinikum der Universität München; 4Klinik für Viszeral- und Endokrine Chirurgie – Campus Innenstadt, Klinikum der Universität München; 5Maria-Theresia-Klinik; Munich, Germany Abstract OBJECTIVE: Strain-elastography Read More
Vitamin D levels in a large Mediterranean cohort: reconsidering normal cut-off values
Marianna Katrinaki,1 Marilena Kampa,2,3 Andrew Margioris,1,4 Elias Castanas,2,3 Niki Malliaraki1 1Laboratory of Clinical Chemistry-Biochemistry, University Hospital, 2Laboratory of Experimental Endocrinology-Clinical Immunology, University Hospital, 3Laboratory of Experimental Endocrinology-Clinical Immunology, University of Crete, School of Medicine, 4Laboratory of Clinical Chemistry, University of Crete, School of Medicine, Heraklion, Crete, Greece Abstract OBJECTIVE: The determination of the normal range Read More
Beneficial effect of dose escalation and surgical debulking in patients with acromegaly treated with somatostatin analogs in a Romanian tertiary care center
Monica Livia Gheorghiu,1,2* Simona Găloiu,1,2* Mădălina Vintilă,1 Mariana Purice,1 Dan Hortopan,1 Anda Dumitraşcu,1 Mihail Coculescu†,1,2 Cătălina Poiană1,2 1“C.I. Parhon” National Institute of Endocrinology, 2“Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania *Authors with equal contribution Abstract BACKGROUND: Somatostatin analogs (SSA) are now considered standard therapy for acromegaly, as primary or adjunctive treatment after pituitary Read More
Salivary testosterone responses to a physical and psychological stimulus and subsequent effects on physical performance in healthy adults
Blair T. Crewther,1,2,3 Liam P. Kilduff,4 Charlie Finn,4,5 Phil Scott,6 Christian J. Cook2,3,4,7 1Institute of Sport – National Research Institute, Warsaw, Poland; 2Hamlyn Centre, Imperial College, London, 3School of Sport Health and Exercise Science Bangor University, Bangor, Wales, 4Applied Sports, Technology, Exercise and Medicine (A-STEM) research centre, School of Engineering, Swansea University, Swansea, 5University of Read More
Which is the best predictor of thyroid cancer: thyrotropin, thyroglobulin or their ratio?
Pinar Yazici,1 Mehmet Mihmanli,1 Emre Bozkurt,1 Feyza Yener Ozturk,2 Mehmet Uludag1 1General Surgery Clinic, 2Endocrinology and Metabolism Institute, Sisli Etfal Training and Research Hospital, Istanbul, Turkey Abstract OBJECTIVE: Since documented incidence of thyroid cancer has been rising over time, in part due to incidental small papillary cancer, several studies have been carried out to investigate the Read More
Clinical impact of strict criteria for selectivity and lateralization in adrenal vein sampling
Alessandro Gasparetto, John F. Angle, Pasha Darvishi, Colbey W. Freeman, Ray G. Norby, Robert M. Carey University of Virginia, USA Abstract INTRODUCTION: Selectivity index (SI) and lateralization index (LI) thresholds determine the adequacy of adrenal vein sampling (AVS) and the degree of lateralization. The purpose of this study was investigate the clinical outcome of patients Read More
Delayed diagnosis of disorder of sex development (DSD) due to P450 oxidoreductase (POR) deficiency
Vasiliki Koika, Anastasia K. Armeni, Neoklis A. Georgopoulos Division of Reproductive Endocrinology, Department of Obstetrics and Gynecology, University of Patras Medical School, Patras, Greece Abstract CASE PRESENTATION: A 36-year old man, operated on for cryptorchidism at the age of 8 years, was referred to the Outpatient Clinic of Reproductive Endocrinology for investigation of infertility. Clinical Read More
Therapeutic trends and outcome of acromegaly: a single center experience over a 40-year period
Olga Karapanou, Marinella Tzanela, Marietta Christoforaki, Lida Papastathopoulou, Paraskevi Moutsatsou, Efi Botoula, Stylianos Tsagarakis Department of Endocrinology, Diabetes and Metabolism, “Evaggelismos” Hospital, Athens, Greece Abstract OBJECTIVE: To evaluate the therapeutic trends and long-term outcome of treatment modalities for acromegaly in our center over a 40-year period. Design: We retrospectively studied 321 acromegalic patients (145 males/176 Read More