Smyth P. PA1, Burns R.1, Smith D. F.1, O? Herlihy C.2 1UCD Conway Institute, UCD, Belfield, Dublin, Ireland, 2National Maternity Hospital, Dublin, Ireland Abstract The relative absence of iodised salt from the Irish diet which latest figures indicate has declined from ~ 4% to <1% of salt sales has resulted in Urinary Iodine (UI) excretion Read More
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INFLUENCE OF THE INTERVAL (24, 48, OR 72 HOURS) BETWEEN THE ADMINISTRATION OF 0.1 MG RECOMBINANT HUMAN THYROTROPIN (RHTSH) AND SUBSEQUENT THYROID RADIOIODINE UPTAKE IN NONTOXIC GOITER PATIENTS. EVALUATION BY A RANDOMIZED DOUBLE-BLINDED TRIAL
Fast S.1, Grupe P.2, Bonnema S.J.1, Heged?s L.1 1Department of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark, 2Department of Nuclear Medicine, Odense University Hospital, Odense, Denmark Abstract Background: Recombinant human thyrotropin (rhTSH) approximately doubles thyroid radioiodine uptake (RAIU) in patients with nontoxic nodular goitre (NTNG), at large independent of rhTSH dose.Aim: To evaluate the Read More
US-GUIDED PERCUTANEOUS RADIOFREQUENCY THERMAL ABLATION FOR THE TREATMENT OF SOLID BENIGN HYPERFUNCTIONING OR COMPRESSIVE THYROID NODULES
Deandrea M., Limone P., Basso E., Mormile A., Ragazzoni F., Gamarra E., Spiezia S., Faggiano A., Colao A., Molinari F., Garberoglio R. Ospedale Mauriziano Umberto I di Torino, UOA di Endocrinologia e Centro per le Malattie della Tiroide Abstract Objectives Aim: of the study was to define the effectiveness and safety of US-guided percutaneous radiofrequency Read More
RADIOFREQUENCY THERMAL ABLATION IN THE TREATMENT OF THYROID NODULES: 2 YEAR FOLLOW-UP
Spiezia S.1, Faggiano A.2, Ramundo V.2, Garberoglio R.3, Caiazzo C.1, Assanti A. P.1, Deandrea M.3, Limone P.P.3, Lombardi G.2, Colao A.2 1Unit of Ultrasound Guided & Neck Pathology Surgery, “S. Maria del Popolo degli Incurabili” Hospital, Naples, Italy, 2Department of Molecular and Clinical Endocrinology and Oncology, “Federico II” University of Naples, Italy, 3Unit of Endocrinology Read More
NO LINK BETWEEN X CHROMOSOME INACTIVATION PATTERN AND SIMPLE GOITRE IN FEMALES. EVIDENCE FROM A TWIN STUDY
Brix T.1, Hansen P.2, Knudsen G.3, Kringen M. K.3, Kyvik K. O.2, Sorensen T. H. I. A.4, Orstavik K. H.5, Heged?s L.1 1Department of Endocrinology and Metabolism, Odense University Hospital,Odense, Denmark, 2The Danish Twin Registry, University of Southern Denmark, Odense, Denmark, 3Faculty Division Rikshospitalet, University of Oslo, Oslo, Norway, 4Danish Epidemiology Science Centre, Institute of Read More
HYPOTHYROIDISM HAS AN ADVERSE EFFECT ON HUMAN SPERMATOGENESIS: A PROSPECTIVE, CONTROLLED STUDY
Krassas G. E.1, Pontikides N.1, Papadopoulou F.1, Tziomalos K.1, Zegeniadou T.1, Hammadeh M.2 1Department of Endocrinology, Diabetes and Metabolism, Panagia General Hospital, Thessaloniki, Greece, 2Department of Obstetrics and Gynaecology, University of Saarland, Homburg Saar, Germany Abstract Little is known about the effects of hypothyroidism on human spermatogenesis. Only few uncontrolled studies have published so far.Aim: Read More
THYROID DYSFUNCTION, AGING AND CARDIOVASCULAR RISK
Borissova A. M., Kovatcheva R., Shinkov A., Atanassova A., Vlahov J., Aslanova N., Dakovska L., Vukov M. University Hospital of Endocrinology, National Center of Medical Information, Medical University Sofia, Bulgaria Abstract Thyroid dysfunction is a known factor for cardiovascular morbidity. It has been shown that both subclinical hypothyroidism and hyperthyroidism increase significantly cardiovascular risk. Material Read More
ASSOCIATION OF ???ROID FUNCTION WITH MEASURES OF ADIPOSITY AND METABOLIC PROFILE IN APPARENTLY HEALTHY INDIVIDUALS
Saltiki K.1, Voidonikola P.2, Mantzou E.3, Stamatelopoulos K.2, Papamichael C.2, Alevizaki M.1 1Endocrine Unit, Dept Clinical Therapeutics, Alexandra Hospital, Athens University School of Medicine, 2Vascular Laboratory, Dept of Medical Therapeutics, Alexandra Hospital, Athens University School of Medicine, 3Endocrine Unit, Evgenidion Hospital, Athens University School of Medicine Abstract Objectives: Although TSH has been positively associated with Read More
DISTURBED ALTERNATIVE SPLICING OF TYPE 1 DEIODINASE IN RENAL CANCER: POTENTIAL ROLE OF SPLICING FACTORS SF2/ASF AND HNRNPA1
Piekielko-Witkowska A.1, Master A.1, Wojcicka A.1, Lampkowska J.1, Poplawski P.1, Brozda I.1, Tanski Z.2, Nauman A.1 1Medical Center of Postgraduate Education, Department of Biochemistry and Molecular Biology, ul. Warsaw, Poland, 2Specialistic Hospital, Ostroleka, Poland Abstract Background and aims: Type 1 deiodinase (D1) catalyses synthesis of triiodothyronine (T3) which regulates the expression of many tumor suppressor Read More
NOVEL PHYSIOLOGICAL IMPLICATIONS OF CO-TRANSPORT OF (SULFATED) IODOTHYRONINES AND TAUROCHOLATE BY LIVER SLC10A1
Visser W. E.1, Wong W. S.1, Friesema E. C. H.1, Geyer J.2, Visser T. J.1 1Internal Medicine, Erasmus MC, Rotterdam, The Netherlands, 2Institute of Pharmacology and Toxicology, Justus-Liebig-University of Giessen, Giessen, Germany Abstract Deiodination is an important metabolic pathway for iodothyronines and their sulfates that takes place intracellularly. Therefore, transport of (sulfated) iodothyronines across the Read More