Author: admin

Schott M.1, Broecker-Preuss M.2, Casati M.3, van Helden J.5, Inomata K.6, Kratzsch J.7, Mann K.2, Camara Mas J.4, Miyazaki N.8, Navarro Moreno M. A.4, Murakami T.6, Yoshimura Noh J.8, Roth H.J.9, Scherbaum A.W.1, Hermsen D.10 1Department of Endocrinology, Diabetes and Rheumatology, University Hospital Duesseldorf, 2 Department of Endocrinology, University Hospital Essen, Essen, Germany, 3A.O. San Read More

Zoenen M.1, Urizar E.2, Vassart G.3, Costagliola S.1 1IRIBHM, Universite Libre de Bruxelles, Campus Erasme, B-1070 Brussels, Belgium, 2Center for Molecular Recognition, Columbia University, New York, USA, 3Service de Genetique Medicale, Hopital Erasme, Brussels, Belgium Abstract The TSH receptor (TSHR) is a G protein-coupled receptor (GPCR) with a division of labor between agonist binding, by Read More

Opitz R., Lorenz C., Trubiroha A., Kloas W. Department of Inland Fisheries, Leibniz-Institute of Freshwater Ecology and Inland Fisheries, Berlin, Germany Abstract function, molecular data on thyroid responses to TSH are still mainly limited to a few mammalian model species. To gain insights into molecular mechanisms of thyroid function in non-mammalian vertebrates, we used real-time Read More

Recacha P.1, Santisteban P.1 1Endocrine and Nervous System physiopathology, Instituto de Investigaciones Biomedicas, CSIC-UAM, Madrid, Spain Abstract The study of the mechanisms by which different cell types are specified from the embryonic germ layers has been the subject of recent investigation. Concerning the thyroid organogenesis, available data are mainly about the expression of Titf1, Foxe1 Read More

Ponto K.A.1, Pitz S.1, Hommel G.1, Kahaly G.J.1 1Gutenberg University, Mainz, Germany Abstract Background: Facial disfigurement of Graves? orbitopathy (GO) is accompanied by restrictions in private and professional life. Aim of this prospective study was to determine the relationship between ocular findings, thyroid function and autoantibodies, quality of life, and working ability in GO.Methods: On Read More

Jurecka-Lubieniecka B.1, Polanska J.2, Kula D.1, Krawczyk A.1, Zebracka – Gala J.1, Gubala E.1, Stechly T.1, Tyszkiewicz T.1, Jarzab B.1 1MSC Memorial Cancer Center and Institute of Oncology, Gliwice, Poland, 2Institute of Automatic Control, Silesian University of Technology, Gliwice, Poland Abstract Background: While the multigene predisposition to Graves disease (GD) is well known, although not Read More

Vannucchi G.1, Campi I.1, Bonomi M.1, Covelli D.2, Dazzi D.2, Currò N.2, Bonara P.2, Persani L.1, Beck-Peccoz P.1, Salvi M.1 1Dept. of Medical Sciences, University of Milan, 1st. Auxologico Italiano IRCCS and Fondazione Ospedale Policlinico IRCCS, Milano, 2Ophthalmology, Internal Medicine, University of Milan Abstract Circulating proinflammatory cytokines and CXCL10 have been reported to be elevated Read More

Van Zeijl C.J.J.1, Surovtseva O.V.1, Mourits M.P.2, Fliers E.1, Wiersinga W.M.1, Boelen A.1 1Department of Endocrinology & Metabolism, Academical Medical Center, University of Amsterdam, The Netherlands, 2Orbita Center, Department of Ophthalmology, Academical Medical Center, University of Amsterdam, The Netherlands Abstract Introduction: TSH receptors (TSHR) expressed by differentiated orbital fibroblasts (DOF) may be involved in the Read More

Antonelli A.1, Fallahi P.1, Ferrari S.M.1, Romagnani P.2, Franceschini S.S.3, Serio M.2, Ferrannini E.1 1Department of Internal Medicine, University of Pisa; Pisa; Italy, 2Department of Clinical Pathophysiology, Endocrinology Unit, University of Florence, Florence, Italy, 3Otorhinolaryngology Unit, University of Pisa-School of Medicine, Pisa, Italy Abstract Objectives & Methods: CXC Th1-chemokines and CCL Th2-chemokines play an important Read More

Godlewska M.1, Gora M.1, 2, Krasuska W.1, Banga J.P.3, Gardas A.1 1Department of Biochemistry and Molecular Biology, Medical Centre of Postgraduate Education, Warsaw, Poland, 2Department of Genetics, Institute of Biochemistry and Biophysics PAS, Warsaw, Poland, 3Division of Gene and Cell Based Therapy, King’s College London School of Medicine, London, UK Abstract The major target autoantigen Read More