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Williams K.1, Cowen R.1, von Wasielewski R.2, Resch J.4, West C.3, Brabant G.4 1School of Pharmaccy, University of Manchester, UK, 2Dept. of Pathology, Medizinische Hochschule Hannover, Germany, 3Dept. Radiation Oncology, Manchester, UK, 4Dept. of Endocrinology, Christie Hospital, Manchester, UK Abstract HIF-1α upregulated in many tumour types appears to be critical for radio- and chemosensitivity in Read More

Van Zeijl C.J.J.1, Surovtseva O.V.1, Mourits M.P.2, Fliers E.1, Wiersinga W.M.1, Boelen A.1 1Department of Endocrinology & Metabolism, Academical Medical Center, University of Amsterdam, The Netherlands, 2Orbita Center, Department of Ophthalmology, Academical Medical Center, University of Amsterdam, The Netherlands Abstract Introduction: TSH receptors (TSHR) expressed by differentiated orbital fibroblasts (DOF) may be involved in the Read More

Antonelli A.1, Fallahi P.1, Ferrari S.M.1, Romagnani P.2, Franceschini S.S.3, Serio M.2, Ferrannini E.1 1Department of Internal Medicine, University of Pisa; Pisa; Italy, 2Department of Clinical Pathophysiology, Endocrinology Unit, University of Florence, Florence, Italy, 3Otorhinolaryngology Unit, University of Pisa-School of Medicine, Pisa, Italy Abstract Objectives & Methods: CXC Th1-chemokines and CCL Th2-chemokines play an important Read More

Godlewska M.1, Gora M.1, 2, Krasuska W.1, Banga J.P.3, Gardas A.1 1Department of Biochemistry and Molecular Biology, Medical Centre of Postgraduate Education, Warsaw, Poland, 2Department of Genetics, Institute of Biochemistry and Biophysics PAS, Warsaw, Poland, 3Division of Gene and Cell Based Therapy, King’s College London School of Medicine, London, UK Abstract The major target autoantigen Read More

Schott M.1, Broecker-Preuss M.2, Casati M.3, van Helden J.5, Inomata K.6, Kratzsch J.7, Mann K.2, Camara Mas J.4, Miyazaki N.8, Navarro Moreno M. A.4, Murakami T.6, Yoshimura Noh J.8, Roth H.J.9, Scherbaum A.W.1, Hermsen D.10 1Department of Endocrinology, Diabetes and Rheumatology, University Hospital Duesseldorf, 2 Department of Endocrinology, University Hospital Essen, Essen, Germany, 3A.O. San Read More

Leite J.L.1, Bufalo N.E.1, Santos R.B.2, Romaldini J.H.2, Ward L.S.1 1Molecular Genetics of Cancer Laboratory, Department of Internal Medicine, Medical Science School – FCM, State University of Campinas – UNICAMP, State of Sao Paulo, Brazil, 2Endocrinology, Pontifica Universidade Catolica de Campinas, Sao Paulo, Brazil Abstract Graves\ disease (GD) is a multifactorial condition presumably provoked by Read More

Kotoula V.1, Charalambous E.1, Koletsa T.1, Pliakos I.1, Karayannopoulou G.1, Karkavelas G.1, Mitsiades S.C.2, Mitsiades N.2, 3 1Dept. of Pathology, School of Medicine, Aristotle University, Thessaloniki, Greece, 2Dept. of Medical Oncology, Dana Farber Cancer Institute, and Dept. of Medicine, Harvard Medical School, Boston MA, USA, 3Memorial Sloan Kettering Cancer Center, New York, USA Abstract Context: Read More

Kalarrytou M.1, Mantzou E.1, Boutsiadis A.1, Loukari E.1, Pitsouni E.2, Duntas L.1 1Endocrine Unit, Evgenidion Hospital, University of Athens, Greece, 2Biomedicall Laboratory, Evgenidion Hospital, University of Athens, Greece Abstract Objective: To determine whether and to what extent the acute hypothyroidism induced by thyroid hormone withdrawal (THW) impairs lipid metabolism, body weight (BW), BMI and blood Read More

Peyrottes I.1, Navarro V.2, Ondo-Mendez A.4, Marcellin D.3, Bellanger L.3, Marsault R.2, Lindenthal S.2, Ettore F.1, Spinel-Gomez C.5, Pourcher T.2 1Department of Pathology, Center Antoine Lacassagne, Nice, France, 2TIRO, CEA DSV-iBEB-SBTN, CAL, University of Nice Sophia Antipolis, Nice, France, 3CEA center of Marcoule (D.M., L.B.), DSV-iBEB-SBTN, Bagnols-sur-Ceze, France, 4TIRO, CEA DSV-iBEB-SBTN, CAL, University of Nice Read More

Motamedi M.1, von Wasielewski R.1, Friesema C.N.E.2, Visser J.T.2, Brabant G.3 1Institut f?r Pathologie, Medizinische Hochschule Hannover, Germany, 2Department of Internal Medicine, EMCR, Rotterdam, Netherlands, 3Dept. of Endocrinology, Christie Hospital, Manchester, UK Abstract Recently direct effects of T3 via the PI3K pathways have been described favoring differentiation and reducing thyroid growth. As thyroid carcinomas loose Read More