Proust-Lemoine E.1, D’ Herbomez M.2, Marchandise X.2, Wémeau J.L.1 1Clinique Endocrinologique Marc Linquette, Lille Hospital, 2Service de Medecine Nucleaire, Hopital Roger Salengro, Lille Abstract Several mechanisms, such as subacute thyroiditis, acquired organification trouble, or massive thyroid destruction, may explain precocious hypothyroidism after radioiodine treatment in Graves disease (GD) … Our purpose was to improve its Read More
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LONG-TERM CONTINUOUS ANTITHYROID TREATMENT OF HYPERTHYROIDISM
Azizi F., Ataie L., Mehrabi Y. Research Institute for Endocrine Sciences, Endocrine Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, I.R. Iran Abstract Objective: To report our experience in a large number of patients with hyperthyroidism following long-term continuous antithyroid therapy. Methods: One thousand and twenty nine patients aged 10-79 (77% female) with diffuse Read More
UNUSUAL PRESENTATION OF EUTHYROID GRAVES OPHTHALMOPATHY IN PREGNANCY
Germain S.2, Dagdelen S.1, Saha S.2, Nelson-Piercy C.2, Stanford M.2, Gilbert J.1, Carrol P.2 1Endocrinology and Diabetes, King’s College Hospital, London, UK, 2Gynecology and Obstetrics, Guys and St Thomas, NHS Trust, London, UK Abstract Background: Euthyroid status is observed in ≈ 20 % patients with Graves ophthalmopathy. During pregnancy, hyperthyroid Graves disease tends to improve Read More
QUALITY OF LIFE IN THYROID PATIENTS: A NEW THYROID-SPECIFIC QUESTIONNAIRE DETECTED CLINICALLY MEANINGFUL DIFFERENCES BETWEEN PATIENTS WITH DISSIMILAR BENIGN THYROID DIAGNOSES
Watt T.1, Rasmussen A.K.1, Heged?s L.2, Bonnema, S.J.2, Groenvold M.3, Bjorner J.B.4, Feldt-Rasmussen U.1 1Dpt. of Endocrinology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark, 2Dpt. of Endocrinology and Metabolism, Odense University Hospital, Odense, Denmark, 3Health Service Research, University of Copenhagen, Copenhagen, Denmark, 4National Research Centre for the Working Environment, Copenhagen, Denmark Abstract Objective: To evaluate quality Read More
THE CONSEQUENCES OF EXPERIENCED BODILY CHANGE ON INTERPERSONAL BEHAVIOUR IN PATIENTS WITH THYROID ASSOCIATED OPHTHALMOPATHY
Jensen A.L.1, Harder I.2 1Department of Medical Endocrinology, Aarhus Hospital, Aarhus University Hospital, Denmark, 2Institute of Public Health, Department of Nursing Science, Faculty of Health Sciences, University of Aarhus, Denmark Abstract Background and Aims: Thyroid Associated Ophthhalmopathy (TAO) is characterized by altered appearance of face and eyes and changed visual function. It is well documented Read More
TSHR AUTOANTIBODIES IN THYROIDECTOMISED PATIENTS WITH GRAVES? DISEASE AND ASSOCIATED OPHTALMOPATHY DECREASE AFTER RETROBULBAR RADIATION THERAPY
Loos U.1, B?sselmann I.2, Schmitt Th.2, Franz C.2 1University Ulm and KreLo GmbH Medical Diagnostics, Ulm, Germany, 2KreLo GmbH Medical Diagnostics, Ulm, Germany Abstract Objective: Graves\ disease (GD) hyperthyroidism provoked by stimulating TSHR autoantibodies (sTRAb) is accompanied in 50 % by thyroid associated ophtalmopathy (TAO). It has been demonstrated that TSHR is expressed in the Read More
RETROBULBAR IRRADIATION FOR GRAVES OPHTHALMOPATHY: A RETROSPECTIVE STUDY, EVALUATING THE EFFICACY OF DOSES BETWEEN 12-20GY
Johnson K. TM1, Loesch C.2, Esser J.1, Mann K.3, Eckstein A.1 1Department of Ophthalmology University of Essen, Germany, 2Institute for Medical Informatics, Biometry and Epidemiology University of Essen, Germany, 3Department of Medicine, Division of Endocrinology University of Essen, Germany Abstract Aim: To investigate differences in the clinical outcome of retrobulbar irradiation at 12, 16 and Read More
RESPONSE TO GLUCOCORTICOID THERAPY IN PATIENTS WITH GRAVES? OPHTHALMOPATHY
Beleslin B., Zarkovic M., Ciric J., Stojkovic M., Savic S., Trbojevic B. Institute of endocrinology, Belgrade, Serbia Abstract Background: Clucocorticoids are treatment od choice for moderate to severe Graves\ ophthalmopathy (GO).Objective: The aim of this study was to evaluate effects of gender, age, smoking, duration of eye disease, duration of hyperthyroidism, Cnical activity score (CAS) Read More
EFFECTS OF RADIOIODINE THERAPY ON THE REACTIVATION OF THYROID-ASSOCIATED ORBITOPATHY: ROLE OF PREVENTIVE TREATMENT WITH STEROIDS
Covelli D.1, Campi I.1, Vannucchi G.1, Dazzi D.1, Currò N.2, Simonetta S.2, Beck-Peccoz P.1, Salvi M.1 1Endocrine Unit, Department of Medical Sciences, Fondazione Ospedale Policlinico IRCCS, University of Milan, 2Ophthalmology, Fondazione Ospedale Policlinico IRCCS, University of Milan Abstract Radioiodine therapy (131I) has been reported to trigger worsening of thyroid-associated orbitopathy (TAO), although pre-treatment with steroids Read More
OPHTHALMOPATHY EXACERBATION/OCCURRENCE DURING RADIOIODINE THERAPY OF GRAVES DISEASE – THE PROSPECTIVE STUDY
Król A.1, Krawczyk A.1, Nowak M.3, Zarudzki L.2, Jurecka-Lubieniecka B.1, Hasse-Lazar K.1, Paliczka-Cieślik E.1, Krajewska J.1, Michalik B.1, Jarząb B.1 1Department of Nuclear Medicine and Endocrine Oncology, MSC Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland, 2Department of Radiodiagnostics, MSC Memorial Cancer Center and Institute of Oncology, Gliwice Branch, Gliwice, Poland, 3Department Read More