{"id":1455,"date":"2026-01-24T08:35:20","date_gmt":"2026-01-24T08:35:20","guid":{"rendered":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/2026\/01\/24\/clinical-course-after-re-operation-for-recurrent-papillary-thyroid-carcinoma-in-the-patients-with-hi\/"},"modified":"2026-07-29T18:37:25","modified_gmt":"2026-07-29T18:37:25","slug":"clinical-course-after-re-operation-for-recurrent-papillary-thyroid-carcinoma-in-the-patients-with-hi","status":"publish","type":"post","link":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/2026\/01\/24\/clinical-course-after-re-operation-for-recurrent-papillary-thyroid-carcinoma-in-the-patients-with-hi\/","title":{"rendered":"CLINICAL COURSE AFTER RE-OPERATION FOR RECURRENT PAPILLARY THYROID CARCINOMA IN THE PATIENTS WITH HIGH STIMULATED THYROGLOBULIN VALUE AFTER TOTAL THYROIDECTOMY WITH REMNANT ABLATION"},"content":{"rendered":"
Jeong J.Y.1<\/sup>, Kim W.G.1<\/sup>, Kim T.Y.1<\/sup>, Kim E.Y.1<\/sup>, Gong G.2<\/sup>, Hong S.J.3<\/sup>, Kim T.M.4<\/sup>, Kim W.B.1<\/sup>, Shong Y.K.1<\/sup><\/div>\n
1<\/sup>Department of Internal Medicine, Asan Medical Center\/ University of Ulsan College of Medicine, Seoul, Korea, 2<\/sup>Department of Pathology, Asan Medical Center University of Ulsan College of Medicine, Seoul, Korea, 3<\/sup>Department of Surgery, Asan Medical Center University of Ulsan College of Medicine, Seoul, Korea, 4<\/sup>Thyroid Cancer Clinic, National Cancer Center Goyang, Korea<\/div>\n
\n

Abstract<\/h2>\n

Backgrounds:<\/strong> Recurrence rate of papillary thyroid carcinoma(PTC) after total thyroidectomy with remnant ablation were reported 10-15%. The primary treatment of recurrent PTC is re-operation because most of recurrences limited in cervical area. However, there were insufficient reports about the clinical course of recurrence and the efficacy of re-operation.
Subjects and methods:<\/strong> Patients with PTC who underwent total thyroidectomy followed by immediate remnant ablation between 1995 and 2003 were studied. Patients showing elevated sTg level at first diagnostic whole body scan (DxWBS), 1 year after remnant ablation comprised basis for this study. We evaluated clinical course of the patients with high sTg value, and the outcome of patients who underwent re-operation for recurrence.
Results:<\/strong> 139 patients had positive sTg value more than 10 ug\/dl. In 92 out of 139 (66%) patients, we found recurrence by various imaging modality and 5 patients had lung metastasis. 65 out of 87 patients with neck recurrence underwent re-operation. sTg level after re-operation were as follows: lesser than 1 ug\/L in 18 (28%), 1-10 ug\/L in 25 (38%) and more than 10 ug\/L in 22 (34%). 15 (23%) patients who underwent re-operation had persistent disease in median 52 months of follow up. In 8 of 15 patients, new lung metastasis was found after re-operation whereas 7 patients had persistent disease in neck.
Conclusion:<\/strong> Re-operation for recurrent PTC could decrease sTg level and achieve clinical remission in more than half cases. However, newly recognized lung metastasis was after re-operation in quite a few patients. <\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Jeong J.Y.1, Kim W.G.1, Kim T.Y.1, Kim E.Y.1, Gong G.2, Hong S.J.3, Kim T.M.4, Kim W.B.1, Shong Y.K.1 1Department of Internal Medicine, Asan Medical Center\/ University of Ulsan College of Medicine, Seoul, Korea, 2Department of Pathology, Asan Medical Center University of Ulsan College of Medicine, Seoul, Korea, 3Department of Surgery, Asan Medical Center University of Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-1455","post","type-post","status-publish","format-standard","hentry","category-journal-articles"],"_links":{"self":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1455","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/comments?post=1455"}],"version-history":[{"count":1,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1455\/revisions"}],"predecessor-version":[{"id":11826,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1455\/revisions\/11826"}],"wp:attachment":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/media?parent=1455"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/categories?post=1455"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/tags?post=1455"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}