{"id":1407,"date":"2026-01-24T08:35:20","date_gmt":"2026-01-24T08:35:20","guid":{"rendered":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/2026\/01\/24\/positive-predictive-values-of-sonographic-features-of-solid-thyroid-nodule\/"},"modified":"2026-07-29T18:33:31","modified_gmt":"2026-07-29T18:33:31","slug":"positive-predictive-values-of-sonographic-features-of-solid-thyroid-nodule","status":"publish","type":"post","link":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/2026\/01\/24\/positive-predictive-values-of-sonographic-features-of-solid-thyroid-nodule\/","title":{"rendered":"POSITIVE PREDICTIVE VALUES OF SONOGRAPHIC FEATURES OF SOLID THYROID NODULE"},"content":{"rendered":"<div class=\"article-authors\">Son E.J., Kim E.K., Kwak J.Y., Hong S.W., Chang H.S.<\/div>\n<div class=\"article-institutes\">Yonsei University, College of Medicine, Seoul, Korea<\/div>\n<div class=\"article-abstract\">\n<h2>Abstract<\/h2>\n<p><strong>Objective:<\/strong> The purpose of this study was to assess the positive predictive value of the suspicious sonographic features of solid nodules of the thyroid. <br \/><strong>Materials and Methods:<\/strong> We evaluated 594 sonographically detected nodules on which the fine needle aspiration biopsy (fNAB) had been performed. Among above, pure cystic lesions, inadequate pathologic results, were excluded. Remaining 530 solid thyroid nodules were analyzed by two radiologists. Each lesion was classified based on four sonographic features that suggested malignancy: microcalcifications; an irregular or microlobulated margin; marked hypoechogenicity; and a shape that was taller than wide. The sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of the each sonographic feature were calculated. <br \/><strong>Results:<\/strong> Final pathologic results showed that 97(18.3%) of 530 nodules were malignant. The positive predictive value for malignancy in each sonographic features were: microcalcifications 38.6% (39\/101); an irregular or microlobulated margin 28.2% (70\/248); marked hypoechogenecity 49.4% (38\/77); taller than wide shape 59.8% (49\/82). In the multivariated analysis, microcalcification (p&lt;0.01, RR=3.115, 95% CI: 1.724-5.628), hypoechogenecity (p&lt;0.01, RR=2.510, 95% CI: 1.290-4.881). The shape of nodule which were taller than wide (p&lt;0.01, RR=7.624, 95% CI: 4.156-13.986) revealed the highest predicitive sonographic finding suggesting malignancy. However, margin is the least significant feature of detection of thyroid malignancy (p=0.27, RR=1.395, 95% CI: 0.777-2.505). <br \/><strong>Conclusion:<\/strong> The three sonographic features of solid thyroid nodule, i.e., micro calcifications, marked hypoechogenecity, a taller than wide shapes are meaningful findings in diagnosing thyroid malignancy. The shape that was taller than wide was the most reliable sonographic feature for predicting malignancy. <\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Son E.J., Kim E.K., Kwak J.Y., Hong S.W., Chang H.S. Yonsei University, College of Medicine, Seoul, Korea Abstract Objective: The purpose of this study was to assess the positive predictive value of the suspicious sonographic features of solid nodules of the thyroid. Materials and Methods: We evaluated 594 sonographically detected nodules on which the fine <a class=\"read-more\" href=\"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/2026\/01\/24\/positive-predictive-values-of-sonographic-features-of-solid-thyroid-nodule\/\">Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-1407","post","type-post","status-publish","format-standard","hentry","category-journal-articles"],"_links":{"self":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1407","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/comments?post=1407"}],"version-history":[{"count":1,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1407\/revisions"}],"predecessor-version":[{"id":11821,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1407\/revisions\/11821"}],"wp:attachment":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/media?parent=1407"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/categories?post=1407"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/tags?post=1407"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}