{"id":1279,"date":"2026-01-24T08:35:20","date_gmt":"2026-01-24T08:35:20","guid":{"rendered":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/2026\/01\/24\/us-guided-percutaneous-radiofrequency-thermal-ablation-for-the-treatment-of-solid-benign-hyperfuncti\/"},"modified":"2026-01-24T08:35:20","modified_gmt":"2026-01-24T08:35:20","slug":"us-guided-percutaneous-radiofrequency-thermal-ablation-for-the-treatment-of-solid-benign-hyperfuncti","status":"publish","type":"post","link":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/2026\/01\/24\/us-guided-percutaneous-radiofrequency-thermal-ablation-for-the-treatment-of-solid-benign-hyperfuncti\/","title":{"rendered":"US-GUIDED PERCUTANEOUS RADIOFREQUENCY THERMAL ABLATION FOR THE TREATMENT OF SOLID BENIGN HYPERFUNCTIONING OR COMPRESSIVE THYROID NODULES"},"content":{"rendered":"
Deandrea M., Limone P., Basso E., Mormile A., Ragazzoni F., Gamarra E., Spiezia S., Faggiano A., Colao A., Molinari F., Garberoglio R.<\/div>\n
Ospedale Mauriziano Umberto I di Torino, UOA di Endocrinologia e Centro per le Malattie della Tiroide<\/div>\n
\n

Abstract<\/h2>\n

Objectives Aim:<\/strong> of the study was to define the effectiveness and safety of US-guided percutaneous radiofrequency (RF) thermal ablation in the treatment of compressive solid benign thyroid nodules.
Methods:<\/strong> 31 patients, not liable to surgery or radioiodine (131I) treatment, underwent RF ablation for benign nodules; a total of 33 nodules were treated (two patients had two nodules treated in the same session): 10 cold nodules and 23 hyperfunctioning. Fourteen
patients complained of compressive symptoms. Nodule volume, thyroid function and compressive symptoms were evaluated before treatment and at 1, 3, and 6 months. US-guided RF ablation was performed using Starbust RITA© needle, with 9 expandable prongs; total exposure time was 6-10 minutes at 95 °C in one area or more of the nodule.
Results:<\/strong> Baseline volume (measured at the time of RF ablation) was 27.7 ? 21.5 ml (mean ? SD) but significantly decreased during follow-up: 19.2 ? 16.2 at 1 month (-32.7% p<0.001), 15.9 ? 14.1 ml at 3 months (-46.4 % p<0.001), 14.6 ? 12.6 ml at 6 months (-50.7% p<0.001). After treatment, all patients with cold nodules remained euthyroid; five patients with hot nodules normalized thyroid function, while the remaining sixteen showed a partial remission of hyperthyroidism. Besides a sensation of heat and a mild swelling of the neck, no major complications were observed. Improvement in compressive symptoms was reported by thirteen patients, with a reduction on severity scale from 6.1 ? 1.4 to 2.2 ? 1.9 (p<0.0001). Hyperfunction was fully controlled in 24% of patients and partially reduced in the others.
Conclusions:<\/strong> RF is an effective and safe tecnique in reducing volume of large benign nodules by about 50% and therefore in reducing compressive symptoms. <\/div>\n","protected":false},"excerpt":{"rendered":"

Deandrea M., Limone P., Basso E., Mormile A., Ragazzoni F., Gamarra E., Spiezia S., Faggiano A., Colao A., Molinari F., Garberoglio R. Ospedale Mauriziano Umberto I di Torino, UOA di Endocrinologia e Centro per le Malattie della Tiroide Abstract Objectives Aim: of the study was to define the effectiveness and safety of US-guided percutaneous radiofrequency Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[45,2,9],"tags":[],"class_list":["post-1279","post","type-post","status-publish","format-standard","hentry","category-volume-7-issue-3","category-journal-articles","category-volume-7"],"_links":{"self":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1279","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/comments?post=1279"}],"version-history":[{"count":0,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1279\/revisions"}],"wp:attachment":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/media?parent=1279"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/categories?post=1279"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/tags?post=1279"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}