{"id":1278,"date":"2026-01-24T08:35:20","date_gmt":"2026-01-24T08:35:20","guid":{"rendered":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/2026\/01\/24\/radiofrequency-thermal-ablation-in-the-treatment-of-thyroid-nodules-2-year-follow-up\/"},"modified":"2026-01-24T08:35:20","modified_gmt":"2026-01-24T08:35:20","slug":"radiofrequency-thermal-ablation-in-the-treatment-of-thyroid-nodules-2-year-follow-up","status":"publish","type":"post","link":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/2026\/01\/24\/radiofrequency-thermal-ablation-in-the-treatment-of-thyroid-nodules-2-year-follow-up\/","title":{"rendered":"RADIOFREQUENCY THERMAL ABLATION IN THE TREATMENT OF THYROID NODULES: 2 YEAR FOLLOW-UP"},"content":{"rendered":"
Spiezia S.1<\/sup>, Faggiano A.2<\/sup>, Ramundo V.2<\/sup>, Garberoglio R.3<\/sup>, Caiazzo C.1<\/sup>, Assanti A. P.1<\/sup>, Deandrea M.3<\/sup>, Limone P.P.3<\/sup>, Lombardi G.2<\/sup>, Colao A.2<\/sup><\/div>\n
1<\/sup>Unit of Ultrasound Guided & Neck Pathology Surgery, “S. Maria del Popolo degli Incurabili” Hospital, Naples, Italy, 2<\/sup>Department of Molecular and Clinical Endocrinology and Oncology, “Federico II” University of Naples, Italy, 3<\/sup>Unit of Endocrinology and Ultrasound, Mauriziano Hospital, Turin, Italy<\/div>\n
\n

Abstract<\/h2>\n

Background:<\/strong> Percutaneous radiofrequency thermal ablation (RTA) has been recently reported to be safe and effective in controlling symptoms of large solid thyroid nodules (TNs). These results were obtained by inducing a TN shrinkage of 52% one month after RTA which was further increased after six months.
Objective:<\/strong> The current study aims at investigating a large cohort of patients with compressive TN two years after RTA.
Patients and Materials:<\/strong> Eighty-five elderly patients (aged >65 yrs) with cytologically benign compressive TNs were prospectively enrolled in the study. RTA was performed by using a RITA © Starburst Talon needle inserted under ultrasonographic real time guide. A two year follow-up was achieved in all patients after RTA. TN size were evaluated by using B-mode ultrasonography. Compressive symptom were also evaluated at each follow-up time. Results: All TNs showed a significant decrease after RTA. Mean TN volume decreased from 24.5+\/-2.2 to 7.6+\/-1.4 ml (p<0.001) one year after RTA and 6.6+\/-1.7 ml (p><0.001) two years after treatment. The mean percent decrease as compared to baseline was 75.9+\/-2.2% and 79.2+\/-2.0% twelve and twenty-four months after RTA, respectively. Compressive symptoms improved in all cases and disappeared in 84%. Neither TN regrowth nor compressive symptom relapse were observed during the follow-up.
Conclusion:<\/strong> RTA induces a stable TN shrinkage in patients with large solid TN. Two years after RTA, TN decrease was unchanged as compared to one year evaluation. In parallel, TN-related compressive symptoms were effectively and stably controlled during the follow-up. <\/div>\n","protected":false},"excerpt":{"rendered":"

Spiezia S.1, Faggiano A.2, Ramundo V.2, Garberoglio R.3, Caiazzo C.1, Assanti A. P.1, Deandrea M.3, Limone P.P.3, Lombardi G.2, Colao A.2 1Unit of Ultrasound Guided & Neck Pathology Surgery, “S. Maria del Popolo degli Incurabili” Hospital, Naples, Italy, 2Department of Molecular and Clinical Endocrinology and Oncology, “Federico II” University of Naples, Italy, 3Unit of Endocrinology Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[45,2,9],"tags":[],"class_list":["post-1278","post","type-post","status-publish","format-standard","hentry","category-volume-7-issue-3","category-journal-articles","category-volume-7"],"_links":{"self":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1278","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/comments?post=1278"}],"version-history":[{"count":0,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1278\/revisions"}],"wp:attachment":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/media?parent=1278"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/categories?post=1278"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/tags?post=1278"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}