{"id":1275,"date":"2026-01-24T08:35:20","date_gmt":"2026-01-24T08:35:20","guid":{"rendered":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/2026\/01\/24\/thyroid-dysfunction-aging-and-cardiovascular-risk\/"},"modified":"2026-01-24T08:35:20","modified_gmt":"2026-01-24T08:35:20","slug":"thyroid-dysfunction-aging-and-cardiovascular-risk","status":"publish","type":"post","link":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/2026\/01\/24\/thyroid-dysfunction-aging-and-cardiovascular-risk\/","title":{"rendered":"THYROID DYSFUNCTION, AGING AND CARDIOVASCULAR RISK"},"content":{"rendered":"
Borissova A. M., Kovatcheva R., Shinkov A., Atanassova A., Vlahov J., Aslanova N., Dakovska L., Vukov M.<\/div>\n
University Hospital of Endocrinology, National Center of Medical Information, Medical University Sofia, Bulgaria<\/div>\n
\n

Abstract<\/h2>\n

Thyroid dysfunction is a known factor for cardiovascular morbidity. It has been shown that both subclinical hypothyroidism and hyperthyroidism increase significantly cardiovascular risk.
Material and Methods:<\/strong> Two thousand four hundred and four subjects (1343 female, mean age 48.68±14.4 y and 1061 male, mean age 46.51±14.49 y, NS), divided into three age groups (?20-44 y, 45-59 y, ?60y) were included in the study. All participants filled a questionnaire form, underwent clinical examination and blood was drawn for TSH, total cholesterol, HDL-cholesterol, LDL-cholesterol and triglycerides.
Results:<\/strong> The observed prevalence of thyroid dysfunction (TD) was 8.51%, 9.7% in women and 7.01% in men, NS. The prevalence of hypothyroidism was 4,7% (6.19% in women and 2.84% in men, NS) and that of hyperthyroidism was 3.8% (3.5% in women and 4.17% in men, NS). Thyroid dysfunction was undiagnosed in 58% of the cases. The prevalence of hypothyroidism increased with age 2-fold in women and 7-fold in men, while hyperthyroidism increased nearly twice in both sexes. The prevalence of dyslipidemia increased with age (p<0,001). The observed prevalence of CVD was 3.5% (84\/2404) – 12 patients (14.3%) with thyroid dysfunction and 72 patients (85.7%) without thyroid dysfunction. A significant correlation was found between age and CVD prevalence – 79.8% of the subjects with CVD were ?60 years of age, p<0,001. Thyroid dysfunction prevalence in subjects with CVD was 74.7% higher than in the group without CVD (14.5% vs. 8.3%). Thyroid dysfunction was 3 times more frequent in men with CVD than in those without (18.2% vs. 6.5%, NS), while the thyroid dysfunction prevalence in female subjects with CVD and without CVD did not differ (10.0% vs. 9.6%).
Conclusion:<\/strong> This is an interesting and important observation that should lead us to more aggressive diagnostic work out and concurrent screening for thyroid disorders.<\/div>\n","protected":false},"excerpt":{"rendered":"

Borissova A. M., Kovatcheva R., Shinkov A., Atanassova A., Vlahov J., Aslanova N., Dakovska L., Vukov M. University Hospital of Endocrinology, National Center of Medical Information, Medical University Sofia, Bulgaria Abstract Thyroid dysfunction is a known factor for cardiovascular morbidity. It has been shown that both subclinical hypothyroidism and hyperthyroidism increase significantly cardiovascular risk. Material Read More<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[45,2,9],"tags":[],"class_list":["post-1275","post","type-post","status-publish","format-standard","hentry","category-volume-7-issue-3","category-journal-articles","category-volume-7"],"_links":{"self":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1275","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/comments?post=1275"}],"version-history":[{"count":0,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/posts\/1275\/revisions"}],"wp:attachment":[{"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/media?parent=1275"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/categories?post=1275"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/peaceful-mccarthy.213-158-90-25.plesk.page\/index.php\/wp-json\/wp\/v2\/tags?post=1275"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}